
PBP3 UPDATE FULL
D - query term matched full text in FDA drug labels. C - query term matched short drug description text. (2012) Crystal Structures of Penicillin-Binding Protein 3 (PBP3).
PBP3 UPDATE UPDATE
B - query term matched disease term in drug contraindications or off-label uses, targets listed in drug bioactivity profiles (not MoA targets), or pharmacologic action descriptions. An Update from the Infectious Diseases Society of America. Ranked result list is annotated with 4 level ranking system ordered from highest to lowest: A - query term matched drug name or synonyms, mechanism of action target, or drug indication. Example search for “HMG-CoA Reductase Inhibitor” FDA EPC term for statin drugs returns list of all statin drugs classified by FDA as HMG-CoA reductase inhibitors. Pharmacologic action search example: Supported pharmacologic action terms are MeSH, FDA, ChEBI action roles.Returned drugs are ranked using the following criteria: top ranked drugs have mechanism of action target Mu-type opioid receptor, next in the list are drugs with potencies measured against this receptor. Target search example: Supported target search terms are HUGO gene symbols, Uniprot accessions and target names, and Swissprot identifiers.Įxample search for drugs targeting Mu-type opioid receptor can be run using either of the.Indicated to treat “Chronic Hepatitis C” followed by drugs For drugs approved after 2012 disease annotations are extracted manually from approved drug labels and mapped to SNOMED-CT concepts. Disease annotations for drugs approved before 2012 originate from OMOP vocabulary mappings. Generic drug names, drug synonyms, trade names terms can be used to search for drugs.Įxample search for Lipitor can query using either “Atorvastatin” or “Lipitor”.A comprehensive list of drug development codes and salt or ester formsĪre also stored in the database and can be used as search terms, for example search for "rosuvastatin" the following terms can be used: "rosuvastatin calcium" or "ZD4522".ĭisease search example: Supported disease terms are SNOMED-CT and OMOP vocabulary terms. Any updates to Flash memory on these devices halt the CPU during the whole operation. Venetoclax Dapagliflozin KEYTRUDA Sacubitril LORBRENA Hydroxychloroquine the selectable division into application and Boot Loader sections. The Latest in Chemistry in Coronavirus Research
